Two US service members were killed and one remains missing after Iranian ballistic missile and drone attacks in Jordan on Friday, military officials said.

The US Central Command (Centcom) said four US service members were medically evacuated to hospitals in Jordan but have since been discharged. Others who suffered minor injuries have returned to duty.

Jordan's military earlier said it had intercepted 10 Iranian missiles fired into its airspace overnight, without reporting any damage.

The US military said it had carried out the seventh consecutive night of strikes on Iran since President Donald Trump declared their temporary ceasefire agreement "over".

The US death toll in the conflict has risen to 16 after an American Navy pilot who went missing earlier this month was declared dead, marking the second increase in the toll this week.

At least 50 people have been killed and more than 500 injured in US strikes over the past three weeks, according to Iranian state media, citing the country's health ministry.

Washington and Tehran struck a preliminary deal to end the war in June, but the agreement unravelled within a month of its signing.

Hostilities have re-escalated over the past week, with the US reimposing a blockade on Iranian ports and Tehran declaring the Strait of Hormuz closed.